Interfering with this UV-induced vitamin A deficiency is a new concept for the prevention of skin cancer and aging. The physiological role of this adaptive response to acute and chronic sun exposure should be further analysed. There are other contributing factors such as heredity and environment. But unprotected exposure to the sun's ultraviolet (UV) rays can cause damage to the skin, eyes, and immune system.
Current data indicate that the vitamin A system is a direct target of both UVB and UVA and participates in an adaptive response to UV exposure. Everybody needs some sun exposure to produce vitamin D (which helps calcium absorption for stronger and healthier bones). We have conducted a series of experiments in order to analyse the effects of UV exposure on the epidermal stores of endogenous vitamin A (retinol and retinyl esters), the activity of enzymes and binding proteins, and some biological parameters such as apoptosis transcription factors expression (cJun) and thymine dimers. Includes unlimited streaming via the Bandcamp app, plus download in mp3, FLAC and more. This complex system may be drastically altered upon ultraviolet light exposure because vitamin A absorbs in the UVB range. For You, Out Of You by Vitamin Sun, released 26 January 2018 1. Human epidermis contains significant amounts of Vitamin A, the enzymes responsible for its metabolism toward either storage or activation, the binding proteins for its protection and specific transport, and the nuclear receptors involved in the vitamin A-induced gene-activity modulation.
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